YMC-Pack Diol

YMC-Pack Diol Capillary Columns

In normal phase mode the YMC-Pack Diol stationary phase is a versatile alternative to silica. The bonded phase’s hydroxyl groups provide good selectivity without excessive retention, since hydrogen bonding with the diol layer is not as strong as with the silanols on a non bonded silica surface. YMC Pack-Diol also provides improved reproducibility when compared with bare silica.

    Diol packings are also suitable for separations using reversed phase techniques or molecular weight determination of proteins by gel filtration.

      YMC-Pack Diol-NP is available packed in capillary columns that are compatible with all Nano and Micro LC-MS systems. Capillary columns are suitable for extremely low sample volumes and low flow rates. They are available either with 1/16" connections (10-32 thread) or with 1/32" connections (6-40 thread).

YMC-Pack Diol

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Features

YMC-Pack Diol starts with a base silica support of exceptional purity with very low residual metal content. The silica purity greatly reduces non-specific sample adsorption, thereby providing excellent sample recovery.

    The high surface area, together with the large number of available sites for interaction of the 1,2-dihydroxypropane ligands, provides high preparative loading.

      Whilst normal phase diol columns can be switched to reversed phase solvents the reverse is not true due to the water in reversed phase solvents wetting the silica surface and making re-equilibration under normal phase conditions impossible.

        Capillary hardware is pressure rated at 690 bar / 10,000 psi. For use with Ekisgent Micro- and Nano LC systems, order columns with 1/32" (6-40 thread) end-fitting

Specifications
  YMC-Pack Diol-NP
Modification 1,2-Dihydroxypropyl
Particle size  5 µm
Pore size  6 nm / 60 Å 120 nm / 120 Å
Surface area 450 m2/g 330 m2/g
pH range 2 - 7.5
Literature